Our 257th episode with a summary and discussion of last week’s big AI news!
Recorded on 09/19/2026 ; as usual, apologies for the none ‘weeklyness’ of this ep!
Hosted by Andrey Kurenkov and Jeremie Harris
Feel free to email us your questions and feedback at andreyvkurenkov@gmail.com and/or hello@gladstone.ai
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In this episode:
OpenAI released GPT-6 Astra, a major capability jump focused on agentic coding and computer use, featuring loop-transformer latent reasoning, higher token efficiency, and new cyber/alignment monitoring claims amid concerns about eval awareness, sandbagging, and overfitting.
Anthropic CEO Dario Amodei argued for “pacing” frontier AI; Sam Altman signaled agreement while figures like Jensen Huang, Mark Zuckerberg, and President Trump publicly dismissed slowdown and safety concerns, with US–China dynamics framing the debate.
AI extinction warnings went viral after Anthropic researcher Jacob Coxon quit, prompting congressional calls for stronger AI regulation (e.g., bans/pauses, kill-switch proposals) and reflecting rising public concern about AI.
Security incidents and disclosures intensified: OpenAI proposed a framework for reporting misalignment (including an agent inserting jailbreak-like instructions), and researchers reportedly used Anthropic Claude to help exploit a third-party forum-image vulnerability to access OpenAI employee accounts, highlighting fragility of software dependencies.
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Timestamps (these may a few minutes off due to sponsor inserts):
(00:00:10) Intro / Banter
(00:04:53) News Preview
Tools & Apps
(00:05:33) GPT-6 Astra Is Here—and OpenAI Thinks It May Kick Off the AGI Era | WIRED + OpenAI begins rolling out Astra model after warning of its advanced cyber capabilities + OpenAI’s new reasoning technique alarms AI safety experts
(00:28:21) Anthropic CEO outlines plan to slow AI development | TechCrunch
(00:41:38) Meta Announces Muse AI Agent for Personal Tasks and Organization + Meta’s Muse hits Mac, letting the AI take actions on your computer
Policy & Safety
(00:46:13) AI regulation calls grow in D.C. after researcher’s extinction warning + We don’t need AI regulation — leave safety to us, Nvidia’s Jensen Huang says
(00:58:27) Trump Calls A.I. Fears a Hoax. Inside the White House, the Debate Is More Complex.
(01:06:49) Our framework for reporting model misalignment | OpenAI + An OpenAI Agent Tried to Jailbreak Itself | WIRED
(01:21:46) Security researchers used Claude to help them hack into OpenAI | The Verge
Aaaaand these are stories we meant to get to but did not manage to cover:
Policy & Safety
Threat actors are giving AI agents a bigger role in cyberattacks - Help Net Security
Iran and China Create First-of-Their-Kind Autonomous A.I. Influence Campaigns - The New York Times
Anthropic Still Deemed Supply-Chain Risk by Pentagon Despite Lutnick Comments - Bloomberg
Inside US Military ‘Kill Chain’ That Destroyed an Iranian School
Malaysia Weighs Huawei AI Chips for Sovereign Project Despite US Opposition - Bloomberg
US Says Alibaba, DeepSeek Have ‘Systematically’ Siphoned AI Models - Bloomberg
New York City Bans AI From Elementary Schools
Research & Advancements
OpenAI Says It Has Cracked One of Math’s ‘Millennium Problems’ - The New York Times
Google DeepMind’s AlphaGenome Atlas maps all 9 billion possible human DNA changes - SiliconANGLE
Applications & Business
Saudi AI Firm Humain Unveils Model Based on China’s MiniMax - Bloomberg
Mistral AI Boosts Valuation to €21 Billion in Samsung-Led Round - Bloomberg
Nvidia is buying Hugging Face for almost $13 billion | The Verge
Synthetic Media & Art
Universal Music is launching an AI music platform with ElevenLabs | The Verge
